Juventus have one foot in the Quarter Finals of the Champions League after a clinical and calculated three goal win away to Celtic in the Round of 16 tie at Parkhead this morning.
Efe Ambrose took his place in the home side's starting lineup to the surprise of many, alongside Emilio Izaguirre in a 4-5-1 formation, while Georgios Samaras was omitted from even the bench after not recovering in time from a hamstring injury.
The Italian champions and current Serie A leaders opted to start with Federico Peluso, their recent acquisition from Atalanta, ahead of in-form Sebastian Giovinco and Paul Pogba. They utilised their traditional 3-5-2 system consistently employed under boss Antonio Conte.
It was la vecchia signora who stunned the parochial and passionate crowd in the east end of Glasgow in the third minute when Alessandro Matri nodded past forward approaching Fraser Forster in the Celtic goal.
Nigerian Efe Ambrose, who only arrived back in Glasgow hours before kick off from the African Cup of Nations was to blame, as he misread an aerial ball, allowing Matri to control the ball and look up to slot past the England number 2.
The goal stunned the Hoops, who started as the better side in the early moments, forcing Gianluigi Buffon into a number of saves prior to the opener.
They responded well, throwing men forward and being comfortable in possession throughout the rest of the first half.
The bianconeri on the other hand seemed content to allow Neil Lennon's men to see the ball, although they were almost made to pay.
Kris Commons had peppered Gianluigi Buffon's goal on a number of occasions, but his shots did not have the power to beat the Italian custodian. Kenyan Victor Wanyama, who scored Celtic's first goal against Barcelona went close heading over from a corner just before the break, giving Celtic plenty of encouragement going into half time.
They continued their positive approach in the second half, retaining possession, and cleverly weathering Juve's counter attacking ploys.
Ambrose then missed a gilt-edged chance after the hour, as he could only direct his unchallenged header from eight yards out directly at Buffon.
After failing to find the much sort-after equaliser, the home side were made to pay in the 77th minute when Matri set up Claudio Marchisio who landed the sucker punch, firing home past Forster's right hand side.
Just when things seemed as if they could not get any worse for Lennon's men, they did six minutes later when Serbian Mirko Vucinic calmly passed the ball home, leaving the majority of the 60,000 crowd to go home desolate.
After the match, Hoops boss Neil Lennon acknowledged that his side will need a football miracle to overturn the deficit in Italy.
"We need a miracle but it's the harsh reality of Champions League football," he told reporters.
The second leg at the Olympic Stadium in Turin will take place on March 6.
Follow on Twitter @MoranShaun